When scientists broke the human genome 2003 – Setting your complete genetic code of a human being – many individuals expected to unlock the secrets of the disease. But Genetics Explained only 10 % of the chance. The remaining 90 % of the environment lies within the environment – and the food plan plays an enormous part.
Around the world, there’s a poor food plan Association Up to at least one in five adults aged 25 or older. In Europe, it’s calculated About half All cardiovascular deaths.
But despite a long time of recommendation about fat, salt or sugar, obesity and dietary disease cutting Waking up. Clearly, Something is missing The way we expect of food.
For years, nutrition has often been produced in easy terms: food and nutrients because the body's constructing blocks. About protein, carbohydrate, fat and vitamins – about 150 known chemicals Overall – has dominated the image. But scientists now guess that our food plan actually provides greater than 26,000 Compounds, most of them are still unnecessary.
This is the place where astronomy provides a useful comparison. Astronomers know that the work of the dark matter ends 27 % of the universe. It doesn’t exclude the sunshine and doesn’t reflect the sunshine, and subsequently it can’t be seen directly, but its gravity effects show that it must exist.
Nutrition Science has the same face. In the case of research, most chemicals are hidden to us in food. We eat them day-after-day, but we have now little guess what they do.
Some experts discuss with these unknown molecules “Nutritional Dark Media”. It is a reminder that just as cosmos is filled with invisible forces, our food plan is filled with hidden chemistry.
When researchers analyze the disease, they see a big selection of food, though no association can often be much like known molecules. This is a dark matter of nutrition – the compounds we eat each day but haven’t been mapped or studied. Some can encourage health, but others may increase the chance of disease. The challenge is thought what’s.
Foodomix
Field of Foodomix That's exactly what. It collects genomics (the role of genes), proteomx (protein), metabolomics (cell activity) and neutrinomics (interaction of genes and food plan).
These approaches are starting to point out how the food plan intensifies greater than calories and vitamins with the body.
For example, take the Mediterranean food plan (fruits, vegetables, whole grains, beans, nuts, olive oil and fish), which is thought about Reduce The risk of heart disease.
But why does it work? A gesture is in a molecule called TMAO (trimethylamine n-oxide)Gut bacteria in pork and eggs produce metabolized compounds. High levels of TMAOs increase the chance of heart disease. But GarlicFor example, accommodates material that stops its production. This is an example of how food plan can discover the balance between health and loss.
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Gut bacteria Also play a crucial role. When compounds reach the colon, germs convert them into latest chemicals that may affect inflammation, immunity and metabolism.
For example, Ellagic acid – found in numerous fruits and nuts – converted through gut bacteria urolithins. It is a gaggle of natural compounds that help keep our microorria (body energy factories) healthy.
This shows how the food is a fancy web of communicating chemicals. One compound can affect many biological mechanisms, which may end up in many others. Diet may even turn or shut down genes Epagnitics – Changes to gene activity that don’t change DNA itself.
History has provided excellent examples of this. For example, during World War II, there have been children born within the Netherlands within the Netherlands. More likely To promote heart disease, later type 2 diabetes and schizophrenia in life. Decading a long time later, scientists found what their moms ate their genes activity – or not ate – while getting pregnant.
Maping of food universe
Projects similar to projects Foodom Project Now they try to list this hidden chemical universe. More than 130,000 molecules Food compounds have already been listed in connecting the technique of human protein, gut microbes and diseases. The purpose is to how the food plan interacts with the body, and to discover which unoccupation is basically essential for health.
It is hoped that by understanding the dark matter of nutrition, we are able to answer questions which have long frustrated nutrition science. Why do some foods work for some people but not others? Why do foods sometimes prevent the disease, and sometimes promote? Which food molecules will be used for the preparation of latest drugs, or latest foods?
We are still to start with. But the message is evident – food on our plate will not be just calories and nutrients, but additionally a large chemical scenario that we are only charting. Just because the mapping of the dark matter of the dark matter is changing our theory concerning the universe, so how can we eat the darkest dietary substance, how we treat the disease and the way we expect of health ourselves.